• Blood cell counting in neonates: a comparison between a low volume micromethod and the standard laboratory method
  • Fabrizio Papa, Mauro Rongioletti, Marco Della Ventura, Francesco Di Turi, Maurizio Cortesi, Patrizio Pasqualetti, Maria Bernardetta Majolini, Valeria Collegiani, Marika Cicchese, Maria Letizia Notarmu 2021-12-10


    Iatrogenic anaemia caused by repeated blood sampling to monitor laboratory parameters can contribute, particularly in neonates, to the need for transfusion. "Point of care" laboratory equipment uses smaller amounts of blood for analytic determinations and could, therefore, help to prevent secondary anaemia. In this study we compared the results of haematological parameters measured using a standard laboratory method and using a "point of care" micromethod, with the aim of validating the use of this latter method in clinical practice The results obtained with the micromethod, compared with those of the conventional method, showed that the ABX-Micros analyser is suffi ciently reliable for the measurement of Hb concentration, but that the RBC and platelet counts need to be interpreted with care. The ABX-MicrosCRP200 analyser's ability to carry out a rapid blood count (70 seconds) can, however, be very important in a neonatal intensive care unit. Indeed, the introduction of a POC analyser in a neonatal intensive care unit could lead to a reduction in iatrogenic anaemia among "critical" neonates10 and a consequent reduction of transfusionsupport with RBC.

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